Washington, D.C. 20549



Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

(Amendment No.     )



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Preliminary Proxy Statement



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Definitive Proxy Statement



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Soliciting Material Pursuant to §240.14a-12

Novus Therapeutics, Inc.

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Important Notice Regarding the Availability of Proxy Materials for the Shareholder Meeting to be held on May 12, 2020 for Novus Therapeutics, Inc. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. We encourage you to access and review all of the important information contained in the proxy materials before voting. To view the proxy statement and annual report, go to www.proxydocs.com/Nvus. To submit your proxy while visiting this site, you will need the 12 digit control number in the box below. Under United States Securities and Exchange Commission rules, proxy materials do not have to be delivered in paper. Proxy materials can be distributed by making them available on the Internet. We have chosen to use these procedures for our 2020 Annual Meeting and need YOUR participation. If you want to receive a paper or e-mail copy of the proxy materials, you must request one by following the instructions below. There is no charge to you for requesting a copy. In order to receive a paper package in time for this year’s annual meeting, please make this request on or before April 27, 2020. You may also request paper or e-mail copies of the proxy materials for all future meetings. Printed or emailed materials may be requested by one of the following methods: INTERNET www.investorelections.com/Nvus You must use the 12 digit control number located in the shaded gray box below. TELEPHONE (866) 648-8133 *E-MAIL paper@investorelections.com * If requesting material by e-mail, please send a blank e-mail with the 12 digit control number (located below) in the subject line. No other requests, instructions or other inquiries should be included with your e-mail requesting material. ACCOUNT NO. SHARES The purpose of the Annual Meeting is to take action on the following proposals: The Board of Directors recommends that you vote “FOR” the following. The Board of Directors recommends that you vote “FOR” the following, and “3 YEARS” on proposal 5. 2. Ratification of the appointment of KMJ Corbin & Company LLP as our Independent registered public accounting firm for the fiscal year ending December 31, 2020. 3. To approve and adopt an amendment to our Certificate of Incorporation to effect a reverse stock split of our common stock, at a ratio ranging from 1 share for 10 shares to 1 share for 30 shares, as determined by our board of directors. 4. Advisory (non-binding) vote to approve the compensation of our named executive officers. 5. Advisory (non-binding) vote on the frequency of future advisory votes to approve executive compensation. 1. Election of Directors Nominees 01 Gregory J. Flesher 02 Gary A. Lyons Date: May 12, 2020 Time: 11:30 A.M. PDT Place: Novus Therapeutics, Inc. 19900 MacArthur Boulevard, Suite 550 Irvine, CA 92612 Company Notice of Annual Meeting Proxy Materials Available to View or Receive: 1. Proxy Statement 2. Annual Report For a Convenient Way to View Proxy Materials _ and _ VOTE Online go to: www.proxydocs.com/Nvus Vote In-Person Instructions: While we encourage stockholders to vote by the means indicated above, a stockholder is entitled to vote in person at our 2020 Annual Meeting. In order to attend the meeting and vote in-person, you will need to bring photo identification and proof of ownership as of the record date, March 16, 2020.