United States securities and exchange commission logo May 30, 2024 David-Alexandre Gros Chief Executive Officer Eledon Pharmaceuticals, Inc. 19800 MacArthur Blvd., Suite 250 Irvine, CA 92612 Re: Eledon Pharmaceuticals, Inc. Registration Statement on Form S-3 Filed May 24, 2024 File No. 333-279711 Dear David-Alexandre Gros: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Lauren Hamill at 303-844-1008 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Shelly Heyduk